BDBM107350 US8592431, 138

SMILES: CCCCc1c(Cc2ccc(cc2)-c2ccccc2-c2nc(=O)o[nH]2)c(=O)n([C@H]2C[C@H](C)O[C@H](C)C2)c2ncnn12

InChI Key: InChIKey=ITPVLKMMBRJIQE-JHDGKUDLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-coenzyme A transporter 1 (AT1) (Homo sapiens (Human))	BDBM107350 (US8592431, 138) Show SMILES CCCCc1c(Cc2ccc(cc2)-c2ccccc2-c2nc(=O)o[nH]2)c(=O)n([C@H]2C[C@H](C)O[C@H](C)C2)c2ncnn12 |r| Show InChI InChI=1S/C31H34N6O4/c1-4-5-10-27-26(29(38)36(30-32-18-33-37(27)30)23-15-19(2)40-20(3)16-23)17-21-11-13-22(14-12-21)24-8-6-7-9-25(24)28-34-31(39)41-35-28/h6-9,11-14,18-20,23H,4-5,10,15-17H2,1-3H3,(H,34,35,39)/t19-,20+,23-	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The binding assay was performed using 22.5 pM [125I]-angiotensin II [manufactured by PerkinElmer, USA] (9 μg) in the presence of AT1 membrane an...				US Patent US8592431 (2013) BindingDB Entry DOI: 10.7270/Q2H70DGX
					More data for this Ligand-Target Pair