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SMILES: Clc1ccc2[nH]c(=O)c(C(=O)\C=C\c3ccccc3)c(-c3ccccc3)c2c1

InChI Key: InChIKey=FYOQQQWDDUOFAL-SDNWHVSQSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107635   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [342-460]/[42-168]


(Homo sapiens (Human))		BDBM107635
PNG
(US9695179, 1)
Show SMILES Clc1ccc2[nH]c(=O)c(C(=O)\C=C\c3ccccc3)c(-c3ccccc3)c2c1
Show InChI InChI=1S/C24H16ClNO2/c25-18-12-13-20-19(15-18)22(17-9-5-2-6-10-17)23(24(28)26-20)21(27)14-11-16-7-3-1-4-8-16/h1-15H,(H,26,28)/b14-11+
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UniChem
US Patent
n/an/a 2.43E+3n/an/an/an/an/a25



ConverGene LLC

US Patent


Assay Description
The interactions between test compounds and BRD4 protein containing both bromodomain 1 and bromodomain 2 were measured with human BRD4 protein with N...

US Patent US9695179 (2017)


BindingDB Entry DOI: 10.7270/Q21G0JF6
More data for this
Ligand-Target Pair