BDBM107727 US8933095, 11
SMILES: COc1cccc(Cn2cc3C[C@H](N)C(=O)N(O)c3n2)c1
InChI Key: InChIKey=BLRMYKGPGPRKFX-LBPRGKRZSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (Homo sapiens (Human)) | BDBM107727 (US8933095, 11) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.93 | n/a | n/a | n/a | n/a | n/a | 37 |
Pfizer Inc. US Patent | Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... | US Patent US8933095 (2015) BindingDB Entry DOI: 10.7270/Q2J9653C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (Homo sapiens (Human)) | BDBM107727 (US8933095, 11) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.93 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ... | US Patent US8598200 (2013) BindingDB Entry DOI: 10.7270/Q2G73CBJ | |||||||||||
More data for this Ligand-Target Pair |