BDBM10796 1-(dimethylamino)-2,3-dihydro-1H-inden-4-yl N,N-dimethylcarbamate::Aminoindan deriv. 32a

SMILES: CN(C)C1CCc2c1cccc2OC(=O)N(C)C

InChI Key: InChIKey=SPYQRYLMKRNKFD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Homo sapiens (Human))	BDBM10796 (1-(dimethylamino)-2,3-dihydro-1H-inden-4-yl N,N-di...) Show SMILES CN(C)C1CCc2c1cccc2OC(=O)N(C)C Show InChI InChI=1S/C14H20N2O2/c1-15(2)12-9-8-11-10(12)6-5-7-13(11)18-14(17)16(3)4/h5-7,12H,8-9H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Teva Pharmaceutical Industries					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...				J Med Chem 45: 5260-79 (2002) Article DOI: 10.1021/jm020120c BindingDB Entry DOI: 10.7270/Q2GQ6W07
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM10796 (1-(dimethylamino)-2,3-dihydro-1H-inden-4-yl N,N-di...) Show SMILES CN(C)C1CCc2c1cccc2OC(=O)N(C)C Show InChI InChI=1S/C14H20N2O2/c1-15(2)12-9-8-11-10(12)6-5-7-13(11)18-14(17)16(3)4/h5-7,12H,8-9H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Teva Pharmaceutical Industries					Assay Description Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....				J Med Chem 45: 5260-79 (2002) Article DOI: 10.1021/jm020120c BindingDB Entry DOI: 10.7270/Q2GQ6W07
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM10796 (1-(dimethylamino)-2,3-dihydro-1H-inden-4-yl N,N-di...) Show SMILES CN(C)C1CCc2c1cccc2OC(=O)N(C)C Show InChI InChI=1S/C14H20N2O2/c1-15(2)12-9-8-11-10(12)6-5-7-13(11)18-14(17)16(3)4/h5-7,12H,8-9H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Teva Pharmaceutical Industries					Assay Description Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....				J Med Chem 45: 5260-79 (2002) Article DOI: 10.1021/jm020120c BindingDB Entry DOI: 10.7270/Q2GQ6W07
					More data for this Ligand-Target Pair