BDBM108072 1‐[(3Z)‐1‐acetyl‐2‐oxoindol‐3‐ylidene]‐3‐aminourea (Compound 12)

SMILES: CC(=O)N1C(=O)C(=NC(=O)NN)c2ccccc12

InChI Key: InChIKey=IZKCOVACKVHRPW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chorismate mutase (MTB CM) (Mycobacterium tuberculosis H37Rv)	BDBM108072 (1‐[(3Z)‐1‐acetyl‐2‐o...) Show SMILES CC(=O)N1C(=O)C(=NC(=O)NN)c2ccccc12 |w:7.7| Show InChI InChI=1S/C11H10N4O3/c1-6(16)15-8-5-3-2-4-7(8)9(10(15)17)13-11(18)14-12/h2-5H,12H2,1H3,(H,14,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	37
Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India					Assay Description The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...				Chem Biol Drug Des 83: 498-506 (2014) Article DOI: 10.1111/cbdd.12265 BindingDB Entry DOI: 10.7270/Q2F76B65
					More data for this Ligand-Target Pair