BDBM108226 1‐methyl‐2‐nitrosobenzene (Substrate 3)
SMILES: Cc1ccccc1N=O
InChI Key: InChIKey=TWLBRQVYXPMCFK-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1-Deoxy-D-xylulose-5-phosphate synthase (DXP synthase)) (Escherichia coli K-12 (Enterobacteria)) | BDBM108226 (1‐methyl‐2‐nitrosobenzene (Subst...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.91E+5 | n/a | n/a | n/a | n/a | 8.0 | 37 |
The Johns Hopkins University School of Medicine, 725 North Wolfe St, Baltimore, MD 21205, USA | Assay Description Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate... | Chembiochem 14: 1309-15 (2013) Article DOI: 10.1002/cbic.201300187 BindingDB Entry DOI: 10.7270/Q2J101T3 | |||||||||||
More data for this Ligand-Target Pair |