BDBM108815 US8604016, 395::US9938267, Cmpd ID 395

SMILES: O=C(Cc1cccc(Cn2cccn2)c1)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1

InChI Key: InChIKey=CODBEKBRCVGESO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108815 (US8604016, 395 | US9938267, Cmpd ID 395) Show SMILES O=C(Cc1cccc(Cn2cccn2)c1)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 Show InChI InChI=1S/C30H30N8O2S/c39-27(19-22-8-2-1-3-9-22)32-26-15-14-25(34-35-26)12-4-5-13-29-36-37-30(41-29)33-28(40)20-23-10-6-11-24(18-23)21-38-17-7-16-31-38/h1-3,6-11,14-18H,4-5,12-13,19-21H2,(H,32,35,39)(H,33,37,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2JS9SQV
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108815 (US8604016, 395 | US9938267, Cmpd ID 395) Show SMILES O=C(Cc1cccc(Cn2cccn2)c1)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 Show InChI InChI=1S/C30H30N8O2S/c39-27(19-22-8-2-1-3-9-22)32-26-15-14-25(34-35-26)12-4-5-13-29-36-37-30(41-29)33-28(40)20-23-10-6-11-24(18-23)21-38-17-7-16-31-38/h1-3,6-11,14-18H,4-5,12-13,19-21H2,(H,32,35,39)(H,33,37,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair