BDBM108816 US8604016, 396::US9938267, Cmpd ID 396

SMILES: CN(Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1)C(=O)OC(C)(C)C

InChI Key: InChIKey=WNQUJQRXLDDBIP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108816 (US8604016, 396 | US9938267, Cmpd ID 396) Show SMILES CN(Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1)C(=O)OC(C)(C)C Show InChI InChI=1S/C33H39N7O4S/c1-33(2,3)44-32(43)40(4)22-25-14-10-13-24(19-25)21-29(42)35-31-39-38-30(45-31)16-9-8-15-26-17-18-27(37-36-26)34-28(41)20-23-11-6-5-7-12-23/h5-7,10-14,17-19H,8-9,15-16,20-22H2,1-4H3,(H,34,37,41)(H,35,39,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2JS9SQV
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108816 (US8604016, 396 | US9938267, Cmpd ID 396) Show SMILES CN(Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1)C(=O)OC(C)(C)C Show InChI InChI=1S/C33H39N7O4S/c1-33(2,3)44-32(43)40(4)22-25-14-10-13-24(19-25)21-29(42)35-31-39-38-30(45-31)16-9-8-15-26-17-18-27(37-36-26)34-28(41)20-23-11-6-5-7-12-23/h5-7,10-14,17-19H,8-9,15-16,20-22H2,1-4H3,(H,34,37,41)(H,35,39,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair