BDBM108896 US8604016, 476::US9938267, Cmpd ID 476

SMILES: O=C(Cc1cccc(CN2CCCCC2=O)c1)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1

InChI Key: InChIKey=ZNISZWYGODMAFN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108896 (US8604016, 476 | US9938267, Cmpd ID 476) Show SMILES O=C(Cc1cccc(CN2CCCCC2=O)c1)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 Show InChI InChI=1S/C32H35N7O3S/c40-28(20-23-9-2-1-3-10-23)33-27-17-16-26(35-36-27)13-4-5-14-30-37-38-32(43-30)34-29(41)21-24-11-8-12-25(19-24)22-39-18-7-6-15-31(39)42/h1-3,8-12,16-17,19H,4-7,13-15,18,20-22H2,(H,33,36,40)(H,34,38,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2JS9SQV
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108896 (US8604016, 476 | US9938267, Cmpd ID 476) Show SMILES O=C(Cc1cccc(CN2CCCCC2=O)c1)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 Show InChI InChI=1S/C32H35N7O3S/c40-28(20-23-9-2-1-3-10-23)33-27-17-16-26(35-36-27)13-4-5-14-30-37-38-32(43-30)34-29(41)21-24-11-8-12-25(19-24)22-39-18-7-6-15-31(39)42/h1-3,8-12,16-17,19H,4-7,13-15,18,20-22H2,(H,33,36,40)(H,34,38,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair