BDBM108905 US8604016, 486::US9938267, Cmpd ID 486

SMILES: CCN(C)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1

InChI Key: InChIKey=BKGPLGLBZJIDBM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108905   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108905 (US8604016, 486 | US9938267, Cmpd ID 486) Show SMILES CCN(C)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C31H35N7O3S/c1-3-38(2)30(41)21-24-13-9-12-23(18-24)20-28(40)33-31-37-36-29(42-31)15-8-7-14-25-16-17-26(35-34-25)32-27(39)19-22-10-5-4-6-11-22/h4-6,9-13,16-18H,3,7-8,14-15,19-21H2,1-2H3,(H,32,35,39)(H,33,37,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2JS9SQV
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108905 (US8604016, 486 | US9938267, Cmpd ID 486) Show SMILES CCN(C)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C31H35N7O3S/c1-3-38(2)30(41)21-24-13-9-12-23(18-24)20-28(40)33-31-37-36-29(42-31)15-8-7-14-25-16-17-26(35-34-25)32-27(39)19-22-10-5-4-6-11-22/h4-6,9-13,16-18H,3,7-8,14-15,19-21H2,1-2H3,(H,32,35,39)(H,33,37,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair