BDBM108916 US8604016, 497::US9938267, Cmpd ID 497

SMILES: CCCNC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1

InChI Key: InChIKey=DLMLJJXSIMKLGG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108916   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108916 (US8604016, 497 | US9938267, Cmpd ID 497) Show SMILES CCCNC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C31H35N7O3S/c1-2-17-32-27(39)20-23-11-8-12-24(18-23)21-29(41)34-31-38-37-30(42-31)14-7-6-13-25-15-16-26(36-35-25)33-28(40)19-22-9-4-3-5-10-22/h3-5,8-12,15-16,18H,2,6-7,13-14,17,19-21H2,1H3,(H,32,39)(H,33,36,40)(H,34,38,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2JS9SQV
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108916 (US8604016, 497 | US9938267, Cmpd ID 497) Show SMILES CCCNC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C31H35N7O3S/c1-2-17-32-27(39)20-23-11-8-12-24(18-23)21-29(41)34-31-38-37-30(42-31)14-7-6-13-25-15-16-26(36-35-25)33-28(40)19-22-9-4-3-5-10-22/h3-5,8-12,15-16,18H,2,6-7,13-14,17,19-21H2,1H3,(H,32,39)(H,33,36,40)(H,34,38,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair