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BDBM108973 US8604016, 555

SMILES: CCOC(=O)NCc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C(C)c4ccccc4)s3)nn2)c1

InChI Key: InChIKey=YGLLUTUPXNTCKH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108973   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutaminase kidney isoform, mitochondrial


(Homo sapiens (Human))
BDBM108973
PNG
(US8604016, 555)
Show SMILES CCOC(=O)NCc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C(C)c4ccccc4)s3)nn2)c1
Show InChI InChI=1S/C31H35N7O4S/c1-3-42-31(41)32-20-23-11-9-10-22(18-23)19-27(39)33-26-17-16-25(35-36-26)14-7-8-15-28-37-38-30(43-28)34-29(40)21(2)24-12-5-4-6-13-24/h4-6,9-13,16-18,21H,3,7-8,14-15,19-20H2,1-2H3,(H,32,41)(H,33,36,39)(H,34,38,40)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



Calithera Biosciences Inc.

US Patent


Assay Description
Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...


US Patent US8604016 (2013)


BindingDB Entry DOI: 10.7270/Q2CC0ZBW
More data for this
Ligand-Target Pair