BDBM109060 US8604016, 644

SMILES: CCCCS(=O)(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCC(=N)CCC(=N)NC(=O)Cc3ccccc3)s2)c1

InChI Key: InChIKey=XKFWFCLZWSDSPV-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109060   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109060 (US8604016, 644) Show SMILES CCCCS(=O)(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCC(=N)CCC(=N)NC(=O)Cc3ccccc3)s2)c1 Show InChI InChI=1S/C31H40N6O4S2/c1-2-3-18-43(40,41)22-25-13-9-12-24(19-25)21-29(39)35-31-37-36-30(42-31)15-8-7-14-26(32)16-17-27(33)34-28(38)20-23-10-5-4-6-11-23/h4-6,9-13,19,32H,2-3,7-8,14-18,20-22H2,1H3,(H2,33,34,38)(H,35,37,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
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