BDBM109064 US8604016, 648::US9938267, Cmpd ID 648

SMILES: Cc1noc(Cc2cccc(CC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccc5)s4)nn3)c2)n1

InChI Key: InChIKey=WQKCSRVDFWJXTL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 109064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109064 (US8604016, 648 | US9938267, Cmpd ID 648) Show SMILES Cc1noc(Cc2cccc(CC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccc5)s4)nn3)c2)n1 Show InChI InChI=1S/C30H30N8O3S/c1-20-31-28(41-38-20)19-23-11-7-10-22(16-23)18-26(39)32-25-15-14-24(34-35-25)12-5-6-13-29-36-37-30(42-29)33-27(40)17-21-8-3-2-4-9-21/h2-4,7-11,14-16H,5-6,12-13,17-19H2,1H3,(H,32,35,39)(H,33,37,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2JS9SQV
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109064 (US8604016, 648 | US9938267, Cmpd ID 648) Show SMILES Cc1noc(Cc2cccc(CC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccc5)s4)nn3)c2)n1 Show InChI InChI=1S/C30H30N8O3S/c1-20-31-28(41-38-20)19-23-11-7-10-22(16-23)18-26(39)32-25-15-14-24(34-35-25)12-5-6-13-29-36-37-30(42-29)33-27(40)17-21-8-3-2-4-9-21/h2-4,7-11,14-16H,5-6,12-13,17-19H2,1H3,(H,32,35,39)(H,33,37,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair