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BDBM109065 US8604016, 649

SMILES: FC(F)(F)Oc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4cccc5CNCc45)nn3)s2)c1

InChI Key: InChIKey=ABLRXHMOFAHQKI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109065   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutaminase kidney isoform, mitochondrial


(Homo sapiens (Human))
BDBM109065
PNG
(US8604016, 649)
Show SMILES FC(F)(F)Oc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4cccc5CNCc45)nn3)s2)c1
Show InChI InChI=1S/C29H28F3N7O3S/c30-29(31,32)42-22-9-3-5-18(13-22)14-25(40)35-28-39-38-27(43-28)10-2-1-8-21-11-12-24(37-36-21)34-26(41)15-19-6-4-7-20-16-33-17-23(19)20/h3-7,9,11-13,33H,1-2,8,10,14-17H2,(H,34,37,41)(H,35,39,40)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



Calithera Biosciences Inc.

US Patent


Assay Description
Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...


US Patent US8604016 (2013)


BindingDB Entry DOI: 10.7270/Q2CC0ZBW
More data for this
Ligand-Target Pair