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SMILES: Cc1nc(cs1)C#Cc1ccc(nc1)-c1cccc(F)c1

InChI Key: InChIKey=IIRMRWPXGDCPBX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109097   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM109097
PNG
(US8609852, 3)
Show SMILES Cc1nc(cs1)C#Cc1ccc(nc1)-c1cccc(F)c1
Show InChI InChI=1S/C17H11FN2S/c1-12-20-16(11-21-12)7-5-13-6-8-17(19-10-13)14-3-2-4-15(18)9-14/h2-4,6,8-11H,1H3
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Similars
US Patent
 2.70 -11.7n/an/an/an/an/an/a25



Merck Sharp & Dohme Corp.

US Patent


Assay Description
Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...

US Patent US8609852 (2013)


BindingDB Entry DOI: 10.7270/Q27M06K3
More data for this
Ligand-Target Pair