BDBM109125 US8609852, 32

SMILES: Cc1nc(cs1)C#Cc1cnc(nc1)C1CCCCC1

InChI Key: InChIKey=SPRGHNYPNLSYRA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109125   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM109125 (US8609852, 32) Show SMILES Cc1nc(cs1)C#Cc1cnc(nc1)C1CCCCC1 Show InChI InChI=1S/C16H17N3S/c1-12-19-15(11-20-12)8-7-13-9-17-16(18-10-13)14-5-3-2-4-6-14/h9-11,14H,2-6H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.80	-11.3	n/a	n/a	n/a	n/a	n/a	n/a	25
Merck Sharp & Dohme Corp. US Patent					Assay Description Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...				US Patent US8609852 (2013) BindingDB Entry DOI: 10.7270/Q27M06K3
					More data for this Ligand-Target Pair