BindingDB logo
myBDB logout

null

SMILES: Cc1nc(cs1)C#Cc1ccc(nc1)-c1c(C)cccc1C

InChI Key: InChIKey=RRCUZIKJDXITAD-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109129   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM109129
PNG
(US8609852, 36)
Show SMILES Cc1nc(cs1)C#Cc1ccc(nc1)-c1c(C)cccc1C
Show InChI InChI=1S/C19H16N2S/c1-13-5-4-6-14(2)19(13)18-10-8-16(11-20-18)7-9-17-12-22-15(3)21-17/h4-6,8,10-12H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 3 -11.6n/an/an/an/an/an/a25



Merck Sharp & Dohme Corp.

US Patent


Assay Description
Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...

US Patent US8609852 (2013)


BindingDB Entry DOI: 10.7270/Q27M06K3
More data for this
Ligand-Target Pair