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SMILES: CCc1ccccc1-c1ccc(cn1)C#Cc1csc(C)n1

InChI Key: InChIKey=PAZNLKQXTFRUII-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109148   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM109148
PNG
(US8609852, 55)
Show SMILES CCc1ccccc1-c1ccc(cn1)C#Cc1csc(C)n1
Show InChI InChI=1S/C19H16N2S/c1-3-16-6-4-5-7-18(16)19-11-9-15(12-20-19)8-10-17-13-22-14(2)21-17/h4-7,9,11-13H,3H2,1-2H3
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Similars
US Patent
 4 -11.4n/an/an/an/an/an/a25



Merck Sharp & Dohme Corp.

US Patent


Assay Description
Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...

US Patent US8609852 (2013)


BindingDB Entry DOI: 10.7270/Q27M06K3
More data for this
Ligand-Target Pair