BDBM109166 US8609852, 73

SMILES: Cc1nc(cs1)C#Cc1ccc([nH+]c1)C1CC2CCC1C2

InChI Key: InChIKey=FGMFRBDGNKBVNJ-UHFFFAOYSA-O

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM109166 (US8609852, 73) Show SMILES Cc1nc(cs1)C#Cc1ccc([nH+]c1)C1CC2CCC1C2 |THB:11:14:17.18:20| Show InChI InChI=1S/C18H18N2S/c1-12-20-16(11-21-12)6-3-13-4-7-18(19-10-13)17-9-14-2-5-15(17)8-14/h4,7,10-11,14-15,17H,2,5,8-9H2,1H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2	-11.9	n/a	n/a	n/a	n/a	n/a	n/a	25
Merck Sharp & Dohme Corp. US Patent					Assay Description Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...				US Patent US8609852 (2013) BindingDB Entry DOI: 10.7270/Q27M06K3
					More data for this Ligand-Target Pair