BDBM109168 US8609852, 75

SMILES: Cc1nc(cs1)C#Cc1ccc(nc1)C1CCCC1

InChI Key: InChIKey=HTMLQNUYALZWPL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109168   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM109168 (US8609852, 75) Show SMILES Cc1nc(cs1)C#Cc1ccc(nc1)C1CCCC1 Show InChI InChI=1S/C16H16N2S/c1-12-18-15(11-19-12)8-6-13-7-9-16(17-10-13)14-4-2-3-5-14/h7,9-11,14H,2-5H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	-11.4	n/a	n/a	n/a	n/a	n/a	n/a	25
Merck Sharp & Dohme Corp. US Patent					Assay Description Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...				US Patent US8609852 (2013) BindingDB Entry DOI: 10.7270/Q27M06K3
					More data for this Ligand-Target Pair