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SMILES: Clc1cccc(Cl)c1NC(=O)NCc1ccnc(c1)-n1[nH]cc(-c2cccnc2)c1=O

InChI Key: InChIKey=AEZFKDJHFYYLFS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109271   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane prolyl 4-hydroxylase


(Homo sapiens (Human))		BDBM109271
PNG
(US8609698, 65)
Show SMILES Clc1cccc(Cl)c1NC(=O)NCc1ccnc(c1)-n1[nH]cc(-c2cccnc2)c1=O
Show InChI InChI=1S/C21H16Cl2N6O2/c22-16-4-1-5-17(23)19(16)28-21(31)26-10-13-6-8-25-18(9-13)29-20(30)15(12-27-29)14-3-2-7-24-11-14/h1-9,11-12,27H,10H2,(H2,26,28,31)
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US Patent
n/an/a 900n/an/an/an/an/an/a



Bayer Intellectual Property GmbH

US Patent


Assay Description
Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...

US Patent US8609698 (2013)


BindingDB Entry DOI: 10.7270/Q2G44NZ8
More data for this
Ligand-Target Pair