BDBM109275 US8609622, 2
SMILES: COc1ccc(Cc2cc(ccc2Cl)[C@@]23OC[C@@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)c(F)c1F
InChI Key: InChIKey=ULTLQRPKEDOYSJ-WRTQPQOASA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM109275 (US8609622, 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.42 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 (Sodium/glucose cotransporter), member 1 (Mus musculus (Mouse)) | BDBM109275 (US8609622, 2) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM109275 (US8609622, 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.65 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 (Sodium/glucose cotransporter), member 1 (Mus musculus (Mouse)) | BDBM109275 (US8609622, 2) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair |