new BindingDB logo
myBDB logout

BDBM109802 US8618299, 20

SMILES: Cc1ccc(COc2ccn(-c3ccc4c5C6CCCN6CCc5n(C)c4c3)c(=O)c2)cn1

InChI Key: InChIKey=XGYFUMNQUJJIGM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109802   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM109802
PNG
(US8618299, 20)
Show SMILES Cc1ccc(COc2ccn(-c3ccc4c5C6CCCN6CCc5n(C)c4c3)c(=O)c2)cn1
Show InChI InChI=1S/C27H28N4O2/c1-18-5-6-19(16-28-18)17-33-21-9-13-31(26(32)15-21)20-7-8-22-25(14-20)29(2)23-10-12-30-11-3-4-24(30)27(22)23/h5-9,13-16,24H,3-4,10-12,17H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
13n/an/an/an/an/an/an/an/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...


US Patent US8618299 (2013)


BindingDB Entry DOI: 10.7270/Q2JW8CJ9
More data for this
Ligand-Target Pair