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BDBM109819 US8618299, 37::US8618299, 38

SMILES: Cn1c2CC3CCCCN3Cc2c2ccc(cc12)-n1ccc(OCc2ccc(F)cn2)cc1=O

InChI Key: InChIKey=JUJDWJHCKVEJBM-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 109819   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM109819
PNG
(US8618299, 37 | US8618299, 38)
Show SMILES Cn1c2CC3CCCCN3Cc2c2ccc(cc12)-n1ccc(OCc2ccc(F)cn2)cc1=O
Show InChI InChI=1S/C27H27FN4O2/c1-30-25-13-21(7-8-23(25)24-16-31-10-3-2-4-20(31)12-26(24)30)32-11-9-22(14-27(32)33)34-17-19-6-5-18(28)15-29-19/h5-9,11,13-15,20H,2-4,10,12,16-17H2,1H3
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GoogleScholar
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PC cid
PC sid
UniChem
US Patent
10n/an/an/an/an/an/an/an/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...


US Patent US8618299 (2013)


BindingDB Entry DOI: 10.7270/Q2JW8CJ9
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM109819
PNG
(US8618299, 37 | US8618299, 38)
Show SMILES Cn1c2CC3CCCCN3Cc2c2ccc(cc12)-n1ccc(OCc2ccc(F)cn2)cc1=O
Show InChI InChI=1S/C27H27FN4O2/c1-30-25-13-21(7-8-23(25)24-16-31-10-3-2-4-20(31)12-26(24)30)32-11-9-22(14-27(32)33)34-17-19-6-5-18(28)15-29-19/h5-9,11,13-15,20H,2-4,10,12,16-17H2,1H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
19n/an/an/an/an/an/an/an/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...


US Patent US8618299 (2013)


BindingDB Entry DOI: 10.7270/Q2JW8CJ9
More data for this
Ligand-Target Pair