BDBM109859 US8609681, 102

SMILES: CCCC(F)(F)C[C@H](NC(=O)N1CCC2(CC2)CC1)C(=O)NC1(CC1)C#N

InChI Key: InChIKey=PJOCENBBWQXQGY-AWEZNQCLSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 109859   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin S (Homo sapiens (Human))	BDBM109859 (US8609681, 102) Show SMILES CCCC(F)(F)C[C@H](NC(=O)N1CCC2(CC2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C19H28F2N4O2/c1-2-3-19(20,21)12-14(15(26)24-18(13-22)6-7-18)23-16(27)25-10-8-17(4-5-17)9-11-25/h14H,2-12H2,1H3,(H,23,27)(H,24,26)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109859 (US8609681, 102) Show SMILES CCCC(F)(F)C[C@H](NC(=O)N1CCC2(CC2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C19H28F2N4O2/c1-2-3-19(20,21)12-14(15(26)24-18(13-22)6-7-18)23-16(27)25-10-8-17(4-5-17)9-11-25/h14H,2-12H2,1H3,(H,23,27)(H,24,26)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM109859 (US8609681, 102) Show SMILES CCCC(F)(F)C[C@H](NC(=O)N1CCC2(CC2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C19H28F2N4O2/c1-2-3-19(20,21)12-14(15(26)24-18(13-22)6-7-18)23-16(27)25-10-8-17(4-5-17)9-11-25/h14H,2-12H2,1H3,(H,23,27)(H,24,26)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin B. This protein is obtained as an inactive enzyme from Sigma, Wies...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair