BDBM11011 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazole deriv. 8::5-(4-methylphenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide

SMILES: Cc1ccc(cc1)C1CC(=NN1C(N)=S)c1cccs1

InChI Key: InChIKey=OVCCLBDMXPMYHZ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11011 (1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...) Show SMILES Cc1ccc(cc1)C1CC(=NN1C(N)=S)c1cccs1 |c:10| Show InChI InChI=1S/C15H15N3S2/c1-10-4-6-11(7-5-10)13-9-12(14-3-2-8-20-14)17-18(13)15(16)19/h2-8,13H,9H2,1H3,(H2,16,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	10	-11.4	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A) (Bos taurus)	BDBM11011 (1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...) Show SMILES Cc1ccc(cc1)C1CC(=NN1C(N)=S)c1cccs1 |c:10| Show InChI InChI=1S/C15H15N3S2/c1-10-4-6-11(7-5-10)13-9-12(14-3-2-8-20-14)17-18(13)15(16)19/h2-8,13H,9H2,1H3,(H2,16,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	50	-10.4	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair