BDBM110112 US8609678, 2-((2-(1H-indol-3-yl)ethyl)(2-hydroxyethyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide [165]

SMILES: OCCN(CCc1c[nH]c2ccccc12)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO

InChI Key: InChIKey=USXZOXONJSKOOH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 110112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM110112 (US8609678, 2-((2-(1H-indol-3-yl)ethyl)(2-hydroxyet...) Show SMILES OCCN(CCc1c[nH]c2ccccc12)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO Show InChI InChI=1S/C24H32N6O4/c31-14-13-30(12-10-18-15-26-21-8-5-4-7-20(18)21)24-27-16-19(17-28-24)23(33)25-11-6-2-1-3-9-22(32)29-34/h4-5,7-8,15-17,26,31,34H,1-3,6,9-14H2,(H,25,33)(H,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	7.4	n/a
Acetylon Pharmaceuticals US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US8609678 (2013) BindingDB Entry DOI: 10.7270/Q25M64BS
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM110112 (US8609678, 2-((2-(1H-indol-3-yl)ethyl)(2-hydroxyet...) Show SMILES OCCN(CCc1c[nH]c2ccccc12)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO Show InChI InChI=1S/C24H32N6O4/c31-14-13-30(12-10-18-15-26-21-8-5-4-7-20(18)21)24-27-16-19(17-28-24)23(33)25-11-6-2-1-3-9-22(32)29-34/h4-5,7-8,15-17,26,31,34H,1-3,6,9-14H2,(H,25,33)(H,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	n/a
Acetylon Pharmaceuticals US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US8609678 (2013) BindingDB Entry DOI: 10.7270/Q25M64BS
					More data for this Ligand-Target Pair