BDBM11049 N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-3-sulfanylpropanamide::reduced monomeric thio of compound 3::reduced thio H3

SMILES: NS(=O)(=O)c1nnc(NC(=O)CCS)s1

InChI Key: InChIKey=RQOYDSTYJOSMPC-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM11049 (N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-3-sulfanylpr...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCS)s1 Show InChI InChI=1S/C5H8N4O3S3/c6-15(11,12)5-9-8-4(14-5)7-3(10)1-2-13/h13H,1-2H2,(H2,6,11,12)(H,7,8,10)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biostrutture e Bioimmagini-CNR					Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...				J Med Chem 49: 5544-51 (2006) Article DOI: 10.1021/jm060531j BindingDB Entry DOI: 10.7270/Q21J9805
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM11049 (N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-3-sulfanylpr...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCS)s1 Show InChI InChI=1S/C5H8N4O3S3/c6-15(11,12)5-9-8-4(14-5)7-3(10)1-2-13/h13H,1-2H2,(H2,6,11,12)(H,7,8,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biostrutture e Bioimmagini-CNR					Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...				J Med Chem 49: 5544-51 (2006) Article DOI: 10.1021/jm060531j BindingDB Entry DOI: 10.7270/Q21J9805
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM11049 (N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-3-sulfanylpr...) Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCS)s1 Show InChI InChI=1S/C5H8N4O3S3/c6-15(11,12)5-9-8-4(14-5)7-3(10)1-2-13/h13H,1-2H2,(H2,6,11,12)(H,7,8,10)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	17	-10.5	n/a	n/a	n/a	n/a	n/a	7.5	22
Istituto di Biostrutture e Bioimmagini-CNR					Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...				J Med Chem 49: 5544-51 (2006) Article DOI: 10.1021/jm060531j BindingDB Entry DOI: 10.7270/Q21J9805
					More data for this Ligand-Target Pair