null
SMILES: Cc1cccc(NC(=O)Nc2ccc(Oc3ccnc(c3)-c3cc(c[nH]3)C(O)=O)cc2F)c1
InChI Key: InChIKey=FPTZKIGUSULXNI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human)) | BDBM110607 (US8614234, 76) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | 7.2 | 25 |
Allergan, Inc. US Patent | Assay Description Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30.mu.g of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered S... | US Patent US8614234 (2013) BindingDB Entry DOI: 10.7270/Q20Z71XF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM110607 (US8614234, 76) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | 7.2 | 25 |
Allergan, Inc. US Patent | Assay Description Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30.mu.g of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered S... | US Patent US8614234 (2013) BindingDB Entry DOI: 10.7270/Q20Z71XF | |||||||||||
More data for this Ligand-Target Pair |