BDBM111094 US9695179, 90

SMILES: Cc1noc(C)c1-c1ccc2[nH]c(=O)c(C(=O)\C=C\c3ccccc3)c(-c3cccnc3)c2c1

InChI Key: InChIKey=XJOXESRMMWKLRI-JLHYYAGUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 111094   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BRD4-BD1-BD2 (Homo sapiens (Human))	BDBM111094 (US9695179, 90) Show SMILES Cc1noc(C)c1-c1ccc2[nH]c(=O)c(C(=O)\C=C\c3ccccc3)c(-c3cccnc3)c2c1 Show InChI InChI=1S/C28H21N3O3/c1-17-25(18(2)34-31-17)20-11-12-23-22(15-20)26(21-9-6-14-29-16-21)27(28(33)30-23)24(32)13-10-19-7-4-3-5-8-19/h3-16H,1-2H3,(H,30,33)/b13-10+	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	25
ConverGene LLC US Patent					Assay Description The interactions between test compounds and BRD4 protein containing both bromodomain 1 and bromodomain 2 were measured with human BRD4 protein with N...				US Patent US9695179 (2017) BindingDB Entry DOI: 10.7270/Q21G0JF6
					More data for this Ligand-Target Pair