BDBM111917 US8623901, 245

SMILES: Cc1ccc(o1)-c1ccccc1Cc1nc2n(ncc2c(=O)[nH]1)C1CCOCC1

InChI Key: InChIKey=KUQVIZZLUDLULO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 111917   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (Homo sapiens (Human))	BDBM111917 (US8623901, 245) Show SMILES Cc1ccc(o1)-c1ccccc1Cc1nc2n(ncc2c(=O)[nH]1)C1CCOCC1 Show InChI InChI=1S/C22H22N4O3/c1-14-6-7-19(29-14)17-5-3-2-4-15(17)12-20-24-21-18(22(27)25-20)13-23-26(21)16-8-10-28-11-9-16/h2-7,13,16H,8-12H2,1H3,(H,24,25,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	7.5	0
Boehringer Ingelheim International GmbH US Patent					Assay Description The PDE9A2 enzymatic activity assay was run as scintillation proximity assay (SPA), in general according to the protocol of the manufacturer (GE Heal...				US Patent US8623901 (2014) BindingDB Entry DOI: 10.7270/Q2Z036TP
					More data for this Ligand-Target Pair