BDBM11267 N-(2-chlorophenyl)-2-({4-[4-methyl-5-(4-methyl-1,3-thiazol-2-yl)-2-(methylsulfanyl)thiophen-3-yl]pyrimidin-2-yl}sulfanyl)acetamide::pyrimidine-containing compound 4

SMILES: CSc1sc(c(C)c1-c1ccnc(SCC(=O)Nc2ccccc2Cl)n1)-c1nc(C)cs1

InChI Key: InChIKey=NNVVKOVHRSDRSQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3C-like proteinase (3CL-PRO) (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM11267 (N-(2-chlorophenyl)-2-({4-[4-methyl-5-(4-methyl-1,3...) Show SMILES CSc1sc(c(C)c1-c1ccnc(SCC(=O)Nc2ccccc2Cl)n1)-c1nc(C)cs1 Show InChI InChI=1S/C22H19ClN4OS4/c1-12-10-30-20(25-12)19-13(2)18(21(29-3)32-19)16-8-9-24-22(27-16)31-11-17(28)26-15-7-5-4-6-14(15)23/h4-10H,11H2,1-3H3,(H,26,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
3C-like proteinase (3CL-PRO) (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM11267 (N-(2-chlorophenyl)-2-({4-[4-methyl-5-(4-methyl-1,3...) Show SMILES CSc1sc(c(C)c1-c1ccnc(SCC(=O)Nc2ccccc2Cl)n1)-c1nc(C)cs1 Show InChI InChI=1S/C22H19ClN4OS4/c1-12-10-30-20(25-12)19-13(2)18(21(29-3)32-19)16-8-9-24-22(27-16)31-11-17(28)26-15-7-5-4-6-14(15)23/h4-10H,11H2,1-3H3,(H,26,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	7.0	25
National Tsing Hua University					Assay Description The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...				J Med Chem 49: 3485-95 (2006) Article DOI: 10.1021/jm050852f BindingDB Entry DOI: 10.7270/Q2R20ZKB
					More data for this Ligand-Target Pair