BDBM11271 N-(4-chlorophenyl)-2-({4-[3-(2-chlorophenyl)-1,2-oxazol-5-yl]pyrimidin-2-yl}sulfanyl)acetamide::pyrimidine-containing compound 8

SMILES: Clc1ccc(NC(=O)CSc2nccc(n2)-c2cc(no2)-c2ccccc2Cl)cc1

InChI Key: InChIKey=UQVHELVNDYDRGX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11271   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3C-like proteinase (3CL-PRO) (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM11271 (N-(4-chlorophenyl)-2-({4-[3-(2-chlorophenyl)-1,2-o...) Show SMILES Clc1ccc(NC(=O)CSc2nccc(n2)-c2cc(no2)-c2ccccc2Cl)cc1 Show InChI InChI=1S/C21H14Cl2N4O2S/c22-13-5-7-14(8-6-13)25-20(28)12-30-21-24-10-9-17(26-21)19-11-18(27-29-19)15-3-1-2-4-16(15)23/h1-11H,12H2,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
3C-like proteinase (3CL-PRO) (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM11271 (N-(4-chlorophenyl)-2-({4-[3-(2-chlorophenyl)-1,2-o...) Show SMILES Clc1ccc(NC(=O)CSc2nccc(n2)-c2cc(no2)-c2ccccc2Cl)cc1 Show InChI InChI=1S/C21H14Cl2N4O2S/c22-13-5-7-14(8-6-13)25-20(28)12-30-21-24-10-9-17(26-21)19-11-18(27-29-19)15-3-1-2-4-16(15)23/h1-11H,12H2,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	7.0	25
National Tsing Hua University					Assay Description The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...				J Med Chem 49: 3485-95 (2006) Article DOI: 10.1021/jm050852f BindingDB Entry DOI: 10.7270/Q2R20ZKB
					More data for this Ligand-Target Pair