null
SMILES: Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2nn(CCCCCCCC(=O)NO)c3ncnc(N)c23)c1
InChI Key: InChIKey=MDNAJFVDTSUEGN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM112876 (US9695181, IIb) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
DOUBLE RIDER MEDICINE CO., LTD. US Patent | Assay Description Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M... | US Patent US9695181 (2017) BindingDB Entry DOI: 10.7270/Q2RX9971 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM112876 (US9695181, IIb) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | n/a | 20 |
DOUBLE RIDER MEDICINE CO., LTD. US Patent | Assay Description Enzymatic activity was tested in 96-well or 384-well flat microwell plate by fluorescence detection and taking Ac-Lys-Tyr-Lys(Ac)-AMC as substrate. T... | US Patent US9695181 (2017) BindingDB Entry DOI: 10.7270/Q2RX9971 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM112876 (US9695181, IIb) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
DOUBLE RIDER MEDICINE CO., LTD. US Patent | Assay Description Inhibition of Compound IIa, IIb, IIc and IId on the Activity of Catalyzing Substrate Phosphorylation of KDR (VEGFR2) Protein Tyrosine Kinase at the M... | US Patent US9695181 (2017) BindingDB Entry DOI: 10.7270/Q2RX9971 | |||||||||||
More data for this Ligand-Target Pair |