null
SMILES: CSc1ccccc1-c1nc2cc3OCCCOc3cc2c(=O)o1
InChI Key: InChIKey=UKNUIQSOZXTIQI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kallikrein-7 (Homo sapiens (Human)) | BDBM113292 (US9695194, 9) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 228 | -9.42 | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK7, Substrate S-2586 (Chromogenics, cat. no. 820894) KLK7 activity was determined at 37° C. in 10 mM Na phosphate ... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymotrypsin-C (Homo sapiens (Human)) | BDBM113292 (US9695194, 9) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 400 | -9.07 | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Chymotrypsin, bovine, 25 ug (Roche, sequence grade), Substrate S-2586 (Chromogenics, cat. no. 82 08 94). Chymotrypsin activity was determi... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM113292 (US9695194, 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 900 | -8.57 | n/a | n/a | n/a | n/a | n/a | 8.3 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Thrombin (Chromogenics, cat. no. 820712), Substrate S-2288 (Chromogenics, cat. no. 82 08 52). Thrombin activity was determined at 37° ... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM113292 (US9695194, 9) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.30E+3 | -8.35 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin G (Homo sapiens (Human)) | BDBM113292 (US9695194, 9) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.30E+3 | -8.35 | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-14 (Homo sapiens (Human)) | BDBM113292 (US9695194, 9) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 1.50E+3 | -8.26 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Homo sapiens (Human)) | BDBM113292 (US9695194, 9) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | >1.00E+4 | >-7.09 | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
SIXERA PHARMA AB US Patent | Assay Description Materials: Trypsin, 100 ug (Roche, sequence grade, Mw 23500), Substrate S-2288 (Chromogenics, cat. no. 820852). Trypsin activity was determined at 3... | US Patent US9695194 (2017) BindingDB Entry DOI: 10.7270/Q2CN723D | |||||||||||
More data for this Ligand-Target Pair |