BDBM113726 US8633226, 850
SMILES: CC(C)NC(=O)N[C@H](C(C)C)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1
InChI Key: InChIKey=NFMFQNYGATXKRO-GCJKJVERSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM113726 (US8633226, 850) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.5 | -12.7 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description For radioligand competition studies, a final concentration of 1x105 THP-1 monocytic leukemia cells are combined with 100 μg of LS WGA PS beads (... | US Patent US8633226 (2014) BindingDB Entry DOI: 10.7270/Q22J69HG | |||||||||||
More data for this Ligand-Target Pair |