BDBM11410 1,1-dioxo-3-[(prop-2-yn-1-ylamino)methyl]-2-(propan-2-yl)-2H-1,7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide::2-(1-Methylethyl)-3-[(2-propynylamino)methyl]-2H-thieno-[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide::2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 17::Compound 17d8

SMILES: CC(C)N1C(CNCC#C)=Cc2cc(sc2S1(=O)=O)S(N)(=O)=O

InChI Key: InChIKey=TXYIDHBKZBJXDG-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM11410 (1,1-dioxo-3-[(prop-2-yn-1-ylamino)methyl]-2-(propa...) Show SMILES CC(C)N1C(CNCC#C)=Cc2cc(sc2S1(=O)=O)S(N)(=O)=O |c:9| Show InChI InChI=1S/C13H17N3O4S3/c1-4-5-15-8-11-6-10-7-12(22(14,17)18)21-13(10)23(19,20)16(11)9(2)3/h1,6-7,9,15H,5,8H2,2-3H3,(H2,14,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd.					Assay Description Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...				Bioorg Med Chem 8: 957-75 (2000) Article DOI: 10.1016/s0968-0896(00)00026-2 BindingDB Entry DOI: 10.7270/Q23B5XC0
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM11410 (1,1-dioxo-3-[(prop-2-yn-1-ylamino)methyl]-2-(propa...) Show SMILES CC(C)N1C(CNCC#C)=Cc2cc(sc2S1(=O)=O)S(N)(=O)=O |c:9| Show InChI InChI=1S/C13H17N3O4S3/c1-4-5-15-8-11-6-10-7-12(22(14,17)18)21-13(10)23(19,20)16(11)9(2)3/h1,6-7,9,15H,5,8H2,2-3H3,(H2,14,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd.					Assay Description The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...				Bioorg Med Chem 8: 957-75 (2000) Article DOI: 10.1016/s0968-0896(00)00026-2 BindingDB Entry DOI: 10.7270/Q23B5XC0
					More data for this Ligand-Target Pair