BDBM11424 2-(3-Hydroxypropyl)-3-(4-morpholinylmethyl)-2H-thieno-[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide::2-(3-hydroxypropyl)-3-(morpholin-4-ylmethyl)-1,1-dioxo-2H-1,7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide::2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 31::Compound 17o1

SMILES: NS(=O)(=O)c1cc2C=C(CN3CCOCC3)N(CCCO)S(=O)(=O)c2s1

InChI Key: InChIKey=WSEPCIDVJMDINU-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11424   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM11424 (2-(3-Hydroxypropyl)-3-(4-morpholinylmethyl)-2H-thi...) Show SMILES NS(=O)(=O)c1cc2C=C(CN3CCOCC3)N(CCCO)S(=O)(=O)c2s1 |t:7| Show InChI InChI=1S/C14H21N3O6S3/c15-25(19,20)13-9-11-8-12(10-16-3-6-23-7-4-16)17(2-1-5-18)26(21,22)14(11)24-13/h8-9,18H,1-7,10H2,(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd.					Assay Description Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...				Bioorg Med Chem 8: 957-75 (2000) Article DOI: 10.1016/s0968-0896(00)00026-2 BindingDB Entry DOI: 10.7270/Q23B5XC0
					More data for this Ligand-Target Pair				3D Structure (docked)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM11424 (2-(3-Hydroxypropyl)-3-(4-morpholinylmethyl)-2H-thi...) Show SMILES NS(=O)(=O)c1cc2C=C(CN3CCOCC3)N(CCCO)S(=O)(=O)c2s1 |t:7| Show InChI InChI=1S/C14H21N3O6S3/c15-25(19,20)13-9-11-8-12(10-16-3-6-23-7-4-16)17(2-1-5-18)26(21,22)14(11)24-13/h8-9,18H,1-7,10H2,(H2,15,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd.					Assay Description The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...				Bioorg Med Chem 8: 957-75 (2000) Article DOI: 10.1016/s0968-0896(00)00026-2 BindingDB Entry DOI: 10.7270/Q23B5XC0
					More data for this Ligand-Target Pair				3D Structure (docked)