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BDBM115164 Ethyl 2-[2-(2-benzyl-5,6-dichloro-1H-benzo[d]imidazol-1-yl)pentanamido] acetate (Compound 9)

SMILES: CCCC(C(=O)NCC(=O)OCC)n1c(Cc2ccccc2)nc2cc(Cl)c(Cl)cc12

InChI Key: InChIKey=NJKINVSSHGFKCS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 115164   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-5 motor protein (KSP)


(Homo sapiens (Human))		BDBM115164
PNG
(Ethyl 2-[2-(2-benzyl-5,6-dichloro-1H-benzo[d]imida...)
Show SMILES CCCC(C(=O)NCC(=O)OCC)n1c(Cc2ccccc2)nc2cc(Cl)c(Cl)cc12
Show InChI InChI=1S/C23H25Cl2N3O3/c1-3-8-19(23(30)26-14-22(29)31-4-2)28-20-13-17(25)16(24)12-18(20)27-21(28)11-15-9-6-5-7-10-15/h5-7,9-10,12-13,19H,3-4,8,11,14H2,1-2H3,(H,26,30)
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PC cid
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UniChem
Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



University of Santiago de Compostela, Jenaro de la Fuente s/n, Campus Vida, Santiago de Compostela 15782 (Spain)



Assay Description
The IC50 measurements were done using a microtubule-activated ATPase kinetic assay according to the manufacturer's instructions. Reactions were ...

Chembiochem 15: 1471-80 (2014)


Article DOI: 10.1002/cbic.201402089
BindingDB Entry DOI: 10.7270/Q29W0D5K
More data for this
Ligand-Target Pair