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BDBM115167 Ethyl 2-[2-(2-benzyl-5,6-dibromo-1H-benzo[d]imidazol-1-yl)-2-cyclopropylacetamido] acetate (Compound 12)

SMILES: CCOC(=O)CNC(=O)C(C1CC1)n1c(Cc2ccccc2)nc2cc(Br)c(Br)cc12

InChI Key: InChIKey=BUEJBFCQDIHDGC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 115167   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-5 motor protein (KSP)


(Homo sapiens (Human))		BDBM115167
PNG
(Ethyl 2-[2-(2-benzyl-5,6-dibromo-1H-benzo[d]imidaz...)
Show SMILES CCOC(=O)CNC(=O)C(C1CC1)n1c(Cc2ccccc2)nc2cc(Br)c(Br)cc12
Show InChI InChI=1S/C23H23Br2N3O3/c1-2-31-21(29)13-26-23(30)22(15-8-9-15)28-19-12-17(25)16(24)11-18(19)27-20(28)10-14-6-4-3-5-7-14/h3-7,11-12,15,22H,2,8-10,13H2,1H3,(H,26,30)
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Similars
Article
PubMed
n/an/a 2.29E+3n/an/an/an/an/an/a



University of Santiago de Compostela, Jenaro de la Fuente s/n, Campus Vida, Santiago de Compostela 15782 (Spain)



Assay Description
The IC50 measurements were done using a microtubule-activated ATPase kinetic assay according to the manufacturer's instructions. Reactions were ...

Chembiochem 15: 1471-80 (2014)


Article DOI: 10.1002/cbic.201402089
BindingDB Entry DOI: 10.7270/Q29W0D5K
More data for this
Ligand-Target Pair