BDBM115175 (−)-Ethyl 2-[2-(2-benzoyl-5,6-dibromo-1H-benzo[d]imidazol-1-yl)-2 cyclopropylacetamido] acetate (Compound 21)::(+)-Ethyl 2-[2-(2-benzoyl-5,6-dibromo-1H-benzo[d]imidazol-1-yl)-2 cyclopropylacetamido] acetate (Compound 20)

SMILES: CCOC(=O)CNC(=O)C(C1CC1)n1c(nc2cc(Br)c(Br)cc12)C(=O)c1ccccc1

InChI Key: InChIKey=IBJQLKWVBDZOPI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 115175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-5 motor protein (KSP) (Homo sapiens (Human))	BDBM115175 ((−)-Ethyl 2-[2-(2-benzoyl-5,6-dibromo-1H-ben...) Show SMILES CCOC(=O)CNC(=O)C(C1CC1)n1c(nc2cc(Br)c(Br)cc12)C(=O)c1ccccc1 Show InChI InChI=1S/C23H21Br2N3O4/c1-2-32-19(29)12-26-23(31)20(13-8-9-13)28-18-11-16(25)15(24)10-17(18)27-22(28)21(30)14-6-4-3-5-7-14/h3-7,10-11,13,20H,2,8-9,12H2,1H3,(H,26,31)	PDB MMDB Reactome pathway B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Santiago de Compostela, Jenaro de la Fuente s/n, Campus Vida, Santiago de Compostela 15782 (Spain)					Assay Description The IC50 measurements were done using a microtubule-activated ATPase kinetic assay according to the manufacturer's instructions. Reactions were ...				Chembiochem 15: 1471-80 (2014) Article DOI: 10.1002/cbic.201402089 BindingDB Entry DOI: 10.7270/Q29W0D5K
					More data for this Ligand-Target Pair
Kinesin-5 motor protein (KSP) (Homo sapiens (Human))	BDBM115175 ((−)-Ethyl 2-[2-(2-benzoyl-5,6-dibromo-1H-ben...) Show SMILES CCOC(=O)CNC(=O)C(C1CC1)n1c(nc2cc(Br)c(Br)cc12)C(=O)c1ccccc1 Show InChI InChI=1S/C23H21Br2N3O4/c1-2-32-19(29)12-26-23(31)20(13-8-9-13)28-18-11-16(25)15(24)10-17(18)27-22(28)21(30)14-6-4-3-5-7-14/h3-7,10-11,13,20H,2,8-9,12H2,1H3,(H,26,31)	PDB MMDB Reactome pathway B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Santiago de Compostela, Jenaro de la Fuente s/n, Campus Vida, Santiago de Compostela 15782 (Spain)					Assay Description The IC50 measurements were done using a microtubule-activated ATPase kinetic assay according to the manufacturer's instructions. Reactions were ...				Chembiochem 15: 1471-80 (2014) Article DOI: 10.1002/cbic.201402089 BindingDB Entry DOI: 10.7270/Q29W0D5K
					More data for this Ligand-Target Pair