BDBM11550 N-hydroxy-2-[(2-methyl-1,1-biphenyl-4-yl)methyl]isothiazolidine-3-carboxamide 1,1-dioxide::N-hydroxy-2-{[4-(2-methylphenyl)phenyl]methyl}-1,1-dioxo-1,2-thiazolidine-3-carboxamide::Sultam Hydroxamate 15c

SMILES: Cc1ccccc1-c1ccc(CN2C(CCS2(=O)=O)C(=O)NO)cc1

InChI Key: InChIKey=QDICWLMZEKDVEQ-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 11550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM11550 (N-hydroxy-2-[(2-methyl-1,1-biphenyl-4-yl)methyl]is...) Show SMILES Cc1ccccc1-c1ccc(CN2C(CCS2(=O)=O)C(=O)NO)cc1 Show InChI InChI=1S/C18H20N2O4S/c1-13-4-2-3-5-16(13)15-8-6-14(7-9-15)12-20-17(18(21)19-22)10-11-25(20,23)24/h2-9,17,22H,10-12H2,1H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...				J Med Chem 47: 2981-3 (2004) Article DOI: 10.1021/jm049833g BindingDB Entry DOI: 10.7270/Q29W0CQB
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM11550 (N-hydroxy-2-[(2-methyl-1,1-biphenyl-4-yl)methyl]is...) Show SMILES Cc1ccccc1-c1ccc(CN2C(CCS2(=O)=O)C(=O)NO)cc1 Show InChI InChI=1S/C18H20N2O4S/c1-13-4-2-3-5-16(13)15-8-6-14(7-9-15)12-20-17(18(21)19-22)10-11-25(20,23)24/h2-9,17,22H,10-12H2,1H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>3.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...				J Med Chem 47: 2981-3 (2004) Article DOI: 10.1021/jm049833g BindingDB Entry DOI: 10.7270/Q29W0CQB
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM11550 (N-hydroxy-2-[(2-methyl-1,1-biphenyl-4-yl)methyl]is...) Show SMILES Cc1ccccc1-c1ccc(CN2C(CCS2(=O)=O)C(=O)NO)cc1 Show InChI InChI=1S/C18H20N2O4S/c1-13-4-2-3-5-16(13)15-8-6-14(7-9-15)12-20-17(18(21)19-22)10-11-25(20,23)24/h2-9,17,22H,10-12H2,1H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>4.95E+3	>-7.23	n/a	n/a	n/a	n/a	n/a	7.5	25
Bristol-Myers Squibb Company					Assay Description The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...				J Med Chem 47: 2981-3 (2004) Article DOI: 10.1021/jm049833g BindingDB Entry DOI: 10.7270/Q29W0CQB
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM11550 (N-hydroxy-2-[(2-methyl-1,1-biphenyl-4-yl)methyl]is...) Show SMILES Cc1ccccc1-c1ccc(CN2C(CCS2(=O)=O)C(=O)NO)cc1 Show InChI InChI=1S/C18H20N2O4S/c1-13-4-2-3-5-16(13)15-8-6-14(7-9-15)12-20-17(18(21)19-22)10-11-25(20,23)24/h2-9,17,22H,10-12H2,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>5.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...				J Med Chem 47: 2981-3 (2004) Article DOI: 10.1021/jm049833g BindingDB Entry DOI: 10.7270/Q29W0CQB
					More data for this Ligand-Target Pair