BDBM11580 1c-meta-Me::5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-(3-methylphenyl)pyrimidin-4-amine::Aminomethylpyrimidine 1cb

SMILES: Cc1cccc(c1)-c1nc(N)c(CN)c(n1)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=BEVMVMIJAOGGEI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11580 (1c-meta-Me | 5-(aminomethyl)-6-(2,4-dichlorophenyl...) Show SMILES Cc1cccc(c1)-c1nc(N)c(CN)c(n1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C18H16Cl2N4/c1-10-3-2-4-11(7-10)18-23-16(14(9-21)17(22)24-18)13-6-5-12(19)8-15(13)20/h2-8H,9,21H2,1H3,(H2,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc.					Assay Description DPP-IV inhibitors were measured for their ability to inhibit DPP-IV mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic a...				Bioorg Med Chem Lett 14: 1491-3 (2004) Article DOI: 10.1016/j.bmcl.2004.01.019 BindingDB Entry DOI: 10.7270/Q22B8W7M
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