BDBM116310 US8637528, OM056
SMILES: COc1cc(N)ccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1
InChI Key: InChIKey=BBEQXRUPYAKWEQ-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 7B (Homo sapiens (Human)) | BDBM116310 (US8637528, OM056) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.27 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Omeros Corporation US Patent | Assay Description The assay method used was a scintillation proximity assay (SPA) (obtained from GE Healthcare, Product Code TRKQ7100), with [3H]-cGMP as the substrate... | US Patent US8637528 (2014) BindingDB Entry DOI: 10.7270/Q29022FT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 7 (Homo sapiens (Human)) | BDBM116310 (US8637528, OM056) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.67 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Omeros Corporation US Patent | Assay Description The assay method used was a scintillation proximity assay (SPA) (obtained from GE Healthcare, Product Code TRKQ7100), with [3H]-cGMP as the substrate... | US Patent US8637528 (2014) BindingDB Entry DOI: 10.7270/Q29022FT | |||||||||||
More data for this Ligand-Target Pair |