null
SMILES: CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CCNCC(=O)N1CCC[C@H]1C#N
InChI Key: InChIKey=KEJZQAMISBJAEB-IBGZPJMESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM11702 ((2S)-Cyanopyrrolidine analogue 18f | 1-[3-[2-[2-Cy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | 8.0 | 37 |
National Health Research Institutes | Assay Description The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro... | J Med Chem 49: 373-80 (2006) Article DOI: 10.1021/jm0507781 BindingDB Entry DOI: 10.7270/Q28W3BJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 2 (Homo sapiens (Human)) | BDBM11702 ((2S)-Cyanopyrrolidine analogue 18f | 1-[3-[2-[2-Cy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Health Research Institutes | Assay Description The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro... | J Med Chem 49: 373-80 (2006) Article DOI: 10.1021/jm0507781 BindingDB Entry DOI: 10.7270/Q28W3BJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 8 (Homo sapiens (Human)) | BDBM11702 ((2S)-Cyanopyrrolidine analogue 18f | 1-[3-[2-[2-Cy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Health Research Institutes | Assay Description The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro... | J Med Chem 49: 373-80 (2006) Article DOI: 10.1021/jm0507781 BindingDB Entry DOI: 10.7270/Q28W3BJH | |||||||||||
More data for this Ligand-Target Pair |