BDBM117068 US8664230, 4

SMILES: CN1CCC(CC1)Oc1ncnc2ccc(nc12)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2F)c1

InChI Key: InChIKey=AYXNKGOCZQARJK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 117068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PI3-kinase class I (Homo sapiens (Human))	BDBM117068 (US8664230, 4) Show SMILES CN1CCC(CC1)Oc1ncnc2ccc(nc12)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2F)c1 Show InChI InChI=1S/C24H21ClF2N6O3S/c1-33-8-6-16(7-9-33)36-24-22-19(29-13-30-24)4-3-18(31-22)14-10-20(23(25)28-12-14)32-37(34,35)21-5-2-15(26)11-17(21)27/h2-5,10-13,16,32H,6-9H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM117068 (US8664230, 4) Show SMILES CN1CCC(CC1)Oc1ncnc2ccc(nc12)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2F)c1 Show InChI InChI=1S/C24H21ClF2N6O3S/c1-33-8-6-16(7-9-33)36-24-22-19(29-13-30-24)4-3-18(31-22)14-10-20(23(25)28-12-14)32-37(34,35)21-5-2-15(26)11-17(21)27/h2-5,10-13,16,32H,6-9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM117068 (US8664230, 4) Show SMILES CN1CCC(CC1)Oc1ncnc2ccc(nc12)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2F)c1 Show InChI InChI=1S/C24H21ClF2N6O3S/c1-33-8-6-16(7-9-33)36-24-22-19(29-13-30-24)4-3-18(31-22)14-10-20(23(25)28-12-14)32-37(34,35)21-5-2-15(26)11-17(21)27/h2-5,10-13,16,32H,6-9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair