BDBM11707 (2S)-Cyanopyrrolidine analogue 18k::3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-N-(1-phenylpropyl)propanamide::3-[2-(2-Cyano-(S)-pyrrolidin-1-yl)-2-oxoethylamino]-N-(1-phenylpropyl)propionamide

SMILES: CCC(NC(=O)CCNCC(=O)N1CCC[C@H]1C#N)c1ccccc1

InChI Key: InChIKey=WGVCCFSNQUSAKL-BHWOMJMDSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11707   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11707 ((2S)-Cyanopyrrolidine analogue 18k | 3-({2-[(2S)-2...) Show SMILES CCC(NC(=O)CCNCC(=O)N1CCC[C@H]1C#N)c1ccccc1 |r| Show InChI InChI=1S/C19H26N4O2/c1-2-17(15-7-4-3-5-8-15)22-18(24)10-11-21-14-19(25)23-12-6-9-16(23)13-20/h3-5,7-8,16-17,21H,2,6,9-12,14H2,1H3,(H,22,24)/t16-,17?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	447	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes					Assay Description The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...				J Med Chem 49: 373-80 (2006) Article DOI: 10.1021/jm0507781 BindingDB Entry DOI: 10.7270/Q28W3BJH
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM11707 ((2S)-Cyanopyrrolidine analogue 18k | 3-({2-[(2S)-2...) Show SMILES CCC(NC(=O)CCNCC(=O)N1CCC[C@H]1C#N)c1ccccc1 |r| Show InChI InChI=1S/C19H26N4O2/c1-2-17(15-7-4-3-5-8-15)22-18(24)10-11-21-14-19(25)23-12-6-9-16(23)13-20/h3-5,7-8,16-17,21H,2,6,9-12,14H2,1H3,(H,22,24)/t16-,17?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes					Assay Description The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...				J Med Chem 49: 373-80 (2006) Article DOI: 10.1021/jm0507781 BindingDB Entry DOI: 10.7270/Q28W3BJH
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM11707 ((2S)-Cyanopyrrolidine analogue 18k | 3-({2-[(2S)-2...) Show SMILES CCC(NC(=O)CCNCC(=O)N1CCC[C@H]1C#N)c1ccccc1 |r| Show InChI InChI=1S/C19H26N4O2/c1-2-17(15-7-4-3-5-8-15)22-18(24)10-11-21-14-19(25)23-12-6-9-16(23)13-20/h3-5,7-8,16-17,21H,2,6,9-12,14H2,1H3,(H,22,24)/t16-,17?/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes					Assay Description The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...				J Med Chem 49: 373-80 (2006) Article DOI: 10.1021/jm0507781 BindingDB Entry DOI: 10.7270/Q28W3BJH
					More data for this Ligand-Target Pair