BDBM117713 US8653087, III-393
SMILES: Fc1ccc(cc1Nc1ncnc2cnc(nc12)N1CCOCC1)C(=O)Nc1cc(ccn1)C(F)(F)F
InChI Key: InChIKey=DBHUIOMOLAVFAS-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
B-RAF V600E (Homo sapiens (Human)) | BDBM117713 (US8653087, III-393) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ... | US Patent US8653087 (2014) BindingDB Entry DOI: 10.7270/Q2CR5S1G | |||||||||||
More data for this Ligand-Target Pair |