BDBM11773 hydroxamate deriv. B19::tert-butyl N-(4-{[(2-chlorophenyl)methyl][1-(hydroxycarbamoyl)ethyl]sulfamoyl}phenyl)carbamate

SMILES: CC(N(Cc1ccccc1Cl)S(=O)(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(=O)NO

InChI Key: InChIKey=NSHZIAZLLPSYOQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase (ChC) (Clostridium histolyticum)	BDBM11773 (hydroxamate deriv. B19 | tert-butyl N-(4-{[(2-chlo...) Show SMILES CC(N(Cc1ccccc1Cl)S(=O)(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(=O)NO Show InChI InChI=1S/C21H26ClN3O6S/c1-14(19(26)24-28)25(13-15-7-5-6-8-18(15)22)32(29,30)17-11-9-16(10-12-17)23-20(27)31-21(2,3)4/h5-12,14,28H,13H2,1-4H3,(H,23,27)(H,24,26)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze					Assay Description The rate of hydrolysis was determined from the change in absorbance at 324 nm using an extinction coefficient, 24700 M-1 cm-1 for FALGPA. Initial vel...				Bioorg Med Chem 8: 637-45 (2000) Article DOI: 10.1016/s0968-0896(99)00316-8 BindingDB Entry DOI: 10.7270/Q2542KT3
					More data for this Ligand-Target Pair